1 School of Community Health and Midwifery, University of Central Lancashire, Preston, England.
2 Department of Biology, Nigerian Army University Biu-Borno.
GSC Biological and Pharmaceutical Sciences, 2026, 35(03), 234-243
Article DOI: 10.30574/gscbps.2026.35.3.0230
Received on 11 May 2026; revised on 17 June 2026; accepted on 19 June 2026
Background: Adolescent nicotine vaping has risen substantially in the United Kingdom following the 2021 market entry of cheap, high-nicotine disposable electronic nicotine delivery systems (ENDS). This review characterizes the neurobiological, social, and regulatory drivers of this youth epidemic to formulate evidence-based policy responses.
Methods: A structured narrative review was conducted across PubMed, MEDLINE, Scopus, CENTRAL, and Google Scholar (January 2016–May 2025). Grey literature was sourced from ASH, NHS Digital, and UK health repositories. Evidence was synthesized using the Behavior Change Wheel framework.
Findings: Adolescent nicotine exposure accelerates α4β2 nicotinic receptor upregulation in the prefrontal cortex and striatum, shortening the transition to physiological dependency relative to adults. Peer descriptive norms, school-corridor visibility, and unmonitored digital marketing (TikTok, Instagram) strongly predict experimentation. Population surveillance reveals socioeconomic gradients where material deprivation correlates with daily use. Single-use disposable devices have outpaced the Tobacco and Related Products Regulations (TRPR) 2016, exacerbated by localized Trading Standards enforcement collapse due to budget contractions.
Conclusion: Current UK legislative frameworks are structurally obsolete. An immediate multi-sectoral intervention is mandatory, including a statutory ban on disposable ENDS, plain packaging with flavor restrictions, high-cost retail licensing, and centrally subsidized enforcement funding.
Adolescent; Vaping; Nicotine Addiction; UK Policy; Social Norms; Health Inequalities
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Cynthia Aghanenu-Ajewole and Jummai Andrew Mbula. Addiction, Social Norms and Policy Gaps: Adolescent Nicotine Vaping in the United Kingdom. GSC Biological and Pharmaceutical Sciences, 2026, 35(03), 234-243. Article DOI: https://doi.org/10.30574/gscbps.2026.35.3.0230.