Some immunological parameters in patients with Mycoplasmal urogenital infection

Background: Mostly isolated from genitourinary tracts, mycoplasmas are slow-growing, picky creatures without a cell wall. While many mycoplasma species are considered typical flora, other species can cause significant genital diseases. The purpose of the current investigation was to ascertain the connections between certain immunological characteristics for urinary genital tract infections (UGTIs) and fastidious bacterial infections (Mycoplasma species and Ureaplasma species).

Married women only (pregnant). For purpose, and to obtain reliable results, the following technique was used: RADIAL IMMUNODIFFUSION (concentration IgG, IgM, IgA, C3, C4). The study includes (30) patients were distributed into three age groups (20-29) year 10 patients, (30 – 39) year 10 patients, (40 – 49) year 10 patients and (15) samples as control samples which were apparently (Health women) pregnant (married).

Results: The result show Concentration of IgA mg/dl in Patients and Control significant difference at p value (0.018*) and it was found that Mean ± SD in patient (370.28 ± 136.82) less than control (456.28 ± 60.88) . Concentration of IgG mg/dl in Patients and Control significant difference at p value (0.000**) and it was found that Mean ± SD in patient (2595.49 ± 708.37) higher than control (2000.67 ± 266.82).

Concentration of IgM mg/dl in Patients and Control significant difference at p value (0.024*) and it was found that Mean ± SD in patient (285.0 ± 80.72) less than control (327.0 ± 38.53). C3 mg/dl Concentration in Patients and Control not significant difference at p value (0.441) and it was found that Mean ± SD in patient (220.95 ± 38.77) higher than control (186.62 ± 38.96).

Concentration of C4 mg/dl in Patients and Control significant difference at p value ((0.001**) and it was found that Mean ± SD in patient (59.63 ± 23.74) higher than control (44.36 ± 6.76). In this study, it was found positive correlation in IgG (0.385*) with IgA and negative correlation in IgM (- 0.441) with IgA. And show positive correlation in IgM with IgG (0.191). Correlation C3 with IgA and IgG is negative correlation (- 0.233, - 0.286) and positive correlation with IgM (0.262). Correlation C4 with IgA and IgG is negative correlation (- 0.260, - 0.156) and positive correlation with IgM (0.348). Correlation C4with C3 show positive correlation (0.370*).