1 Department of Biology, College of Education for Pure Sciences, Al-Muthanna University, Iraq.
2 College of Medicine, University of Babylon, Iraq.
3 Veterinary Medicine College, Al-Muthanna University, Iraq.
Research Article
GSC Biological and Pharmaceutical Sciences, 2025, 32(01), 160-164
Article DOI: 10.30574/gscbps.2025.32.1.0273
Received on 01 June 2025; revised on 08 July 2025; accepted on 10 July 2025
Urologic malignancies are the heterogeneous neoplasms which showed as the most common in the tumors incidence rate of the world.
In this prospective cross-sectional study involved a total of (50) patients with urological tumors consist of (35) males and (15) females. The collected group of patients is distributed as the following; 23 with bladder tumor, 17 with prostate tumors, and 10 with renal tumors. Their ages ranged from (9-88) years. The biopsy was collected from each patient during the visiting of the urological surgery unit of Al-Sader Teaching Hospital-Najaf- Iraq during the period (November 2018 to October 2019).
CD8+ counts among urologic cancers (bladder, prostate, and kidney), showed a significant difference (P value = 0.05), Also, it gives an indication that the immune response in relation to intra-tumoral CD8+ T cells exhibits a disparity by the tumor site. The highest mean of CD8+ TILs counts was in bladder (101.6±69.8) followed by prostate (85.7±36.4) and kidney (49.6±34.4).
It was concluded as there is a spatial heterogeneity in counts of CD8+TILs in urological tumor sites (bladder, prostate, and kidney).
Tumor; CD8; Bladder; Prostate; Kidney
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Fouad Qasim Jubair Al-Zayadi, Ifad Kerim Alshibly, Ammad Hasan Mahmood, Mohenned Alsaadawi and Mohamed Baqer Hussein Almosawi. A comparative evaluation of tumor-infiltrating cytotoxic t cells among human urological tumors. GSC Biological and Pharmaceutical Sciences, 2025, 32(1), 160-164. Article DOI: https://doi.org/10.30574/gscbps.2025.32.1.0273