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Research and review articles are invited for publication in September 2026 - Vol. 36, Issue 3 

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Evaluation of blood glucose lowering activity of Coffea robusta leaf extract in mice induced by alloxan

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  • Evaluation of Blood Glucose Lowering Activity of Coffea Robusta Leaf Extract In Mice Induced By Alloxan
  • Evaluation of blood glucose lowering activity of Coffea robusta leaf extract in mice induced by alloxan

Rudi Kartika *, Bohari, Subur P. Pasaribu, Aman Sentosa Panggabean, Daniel and Dirgarini Julia Nurlianti

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University, Jl. Barong Tongkok No. 4 Kampus Gn. Kelua Samarinda Telp. 0541-74915.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2025, 31(02), 017-021.
Article DOI: 10.30574/gscbps.2025.31.2.0119
DOI url: https://doi.org/10.30574/gscbps.2025.31.2.0119
Received on 10 February 2025; revised on 17 March 2025; accepted on 20 March 2025
An investigation of the antidiabetic activity of coffee leaf (Coffearobusta) extract in ethanol with doses 13,95, 27,9 and 55,8 mg/kg BW given orally to white male mice. Measurement of the blood glucose level was done day to-0, 8 and 18 using glucometer and glucotest strip. Doses variation of the ethanol extract coffee leaf  showed that the dose of  27,9 mg/kg BW gave the best antidiabetic activity 59,61%. This experiment showed gave the best antidiabetic activity result gift ethanol extract coffee leaf. And Phytochemical screening ofthe ethanol extract coffee leaf showed the presence of alkaloids, phenols, saponnins, flavonoids and triterpenoids.
Coffea leaf; Blood glucose; Mice; Alloxan
https://gscbps.gsconlinepress.com/sites/default/files/fulltext_pdf/GSCBPS-2025-…

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Rudi Kartika, Bohari, Subur P. Pasaribu, Aman Sentosa Panggabean, Daniel and Dirgarini Julia Nurlianti. Evaluation of blood glucose lowering activity of Coffea robusta leaf extract in mice induced by alloxan. GSC Biological and Pharmaceutical Sciences, 2025, 31(2), 017-021. Article DOI: https://doi.org/10.30574/gscbps.2025.31.2.0119


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