1 Department of Histology and Pathology, College of Veterinary Medicine, Al-Shatrh University, The-Qar ,64007, Iraq.
2 Department of Pathological analysis, College of Science, Al-Qasim Green University, Babylon, 51013, Iraq.
3 Department of medical biotechnology, College of biotechnology, Al-Qasim Green University, Babylon, 51013, Iraq.
4 Department of medical physiology, Hammurabi College of Medicine, university of Babylon, Babylon, 51002, Iraq.
Research Article
GSC Biological and Pharmaceutical Sciences, 2024, 29(01), 265–276.
Article DOI: 10.30574/gscbps.2024.29.1.0398
Received on 11 September 2024; revised on 24 October 2024; accepted on 26 October 2024
Background: A total of 30(100%) cases of diabetes mellitus DM were collected from a private laboratory during the period from October 2023 to February 2024, compared with 30 control to evaluate several parameters in a case-control study.
The demographic information of sex distribution for DM cases appear 16 (53%) male and 14(47%) and the mean±SD of the age was 45.6±14.7 compared to the control 33.6±10.5 which reveals a significant at P = 0.0006. The mean±SD of the BMI was 29±6.4 in DM cases compared to the control 25.8±3.4 which reveals a significant difference at P = 0.0187.
Distribution of DM types appears in 16(53%), and 14(47%) cases of DM type 1 and 2 respectively with no significant difference between the two study groups. The mean±SD of HbA1c Level with DM Patients and was 9.2±2.8 compared to the control 5.6±0.9 which appeared a significant at P = 0.0002.
Methods: Evaluation of C-peptide Level appears the mean±SD of the C-peptide for DM cases was 5.7±4.5 compared to the control 3.3±2.4. this case-control study appeared a significant difference at P = 0.0125. RBS Level mean±SD of DM cases was 275.7±121.5 compared to the control 103.7±16.6. this case-control study appeared significant at P = 0.0001. The distribution of DM cases in blood groups O+, A+, B+, AB+, AB-, and O- was 10(33.3%), 8(26.7%), 5(16.7%), 3(10%), 3(10%), 1(3.3%), respectively.
Results: All the cases in the present study show negative results for rheumatoid factor and there is no correlation between RF and DM. 2(7%) DM cases have a cardiac problem while the other 28(93%) don’t suffer from any cardiac problem. Relationship between COVID-19 and DM Type-1 Patients appears 15(50%) have positive COVID-19, 12(40%) has DM type 1 and 3(10%) has DM type-2.
Conclusion: The study was concluded an appositive relationship between age, HbA1c, C-peptide, RBS, O+ and A+ blood groups and developments of diabetes mellitus.
Diabetes; C-peptide; Blood groups; Covid-19
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Iman Jaber Hasan, karrar salih Mahdi, Mohammed A. Dabbi, Rusul Hamed Obaid and Zainab Mohammed Abass. Evaluation of HbA1c, C-peptide and Rf in DM patients related to COVID-19, ABO group and BMI in Babylon, Iraq. GSC Biological and Pharmaceutical Sciences, 2024, 29(1), 265-276. Article DOI: https://doi.org/10.30574/gscbps.2024.29.1.0398