1 Shambhunath Institute of Pharmacy, Jhalwa, Prayagraj, Uttar Pradesh, India-211012.
2 Lutawan Institute of Pharmacy, Sakara Jaitpura, Ghazipur, Uttar Pradesh, India-233001.
Research Article
GSC Biological and Pharmaceutical Sciences, 2019, 07(02), 052–059.
Article DOI: 10.30574/gscbps.2019.7.2.0066
Received on 14 April 2019; revised on 11 May 2019; accepted on 14 May 2019
This review focuses on the design, synthesis and pharmacological effects of non-steroidal anti-inflammatory (NSAIDs) mefenamic acid which is an anthranilic acid derivative. Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain. Exploitation of the prodrug approach has the potential to achieve a reduction of mefenamic acid GI (gastrointestinal) intolerance, enhance its bioavailability, mask its unpleasant sensation and prolong its duration of action. Mefenamic acid, an effective NSAID has always been used as an anti-inflammatory and analgesic agent. A brief note on various marketed formulations of mefenamic acid provides an insight of the potential capability of this drug and its future scope.
Anti-inflammatory drugs; Mefenamic acid; Rheumatoid arthritis; Dosage formulations
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Srivastava Rajat, Mishra Manoj Kumar, Patel Amit Kumar, Singh Abhishek and Kushwaha Krishna. An insight of non-steroidal anti-inflammatory drug mefenamic acid: A review. GSC Biological and Pharmaceutical Sciences, 2019, 7(2), 052-059. Article DOI: https://doi.org/10.30574/gscbps.2019.7.2.0066