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Research and review articles are invited for publication in September 2026 - Vol. 36, Issue 3 

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Bioactive component analysis of aqueous seed extract of Aframomum melengueta

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  • Bioactive component analysis of aqueous seed extract of Aframomum melengueta

Uche Emmanuel Olunkwa 1, *, Kizito Munachiso Enyereibenyem Iheanacho 1, Chidi Uzoma Igwe 1, Linus Ahuwaraeze Nwaogu 1 and Juliet Nkeiru Iheanacho 2

1 Department of Biochemistry, Federal University of Technology, P.M.B. 1526, Owerri, Nigeria.
2 National Veterinary Research Institute, Vom, Jos, Nigeria.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 25(02), 249–272.
Article DOI: 10.30574/gscbps.2023.25.2.0458
DOI url: https://doi.org/10.30574/gscbps.2023.25.2.0458
Received on 24 September 2023; revised on 14 November 2023; accepted on 16 November 2023
Objective: Aframomum melegueta Schum (Zingiberaceae) is widely cultivated for its valuable seeds in the tropical region of Africa. This study identified the bioactive components present in aqueous seed extract of Aframomum melengueta
Methodology: Aqueous seed extract of Aframomum melengueta was qualitatively and quantitatively analyzed using Fourier-transform infrared spectroscopy (FTIR) and Gas chromatography coupled with flame ionization detector (GCFID).
Result: FTIR identified twelve organic functional groups of –OH, -NH2, CH, -NH3+, -CH3, -OH, -N=C=O, -C≡N, -C=C=C, -NH, -CH3 and -1,3,5-trisubstituted benzenes. GCFID identified fifteen bioactive components namely kaemferol, naringenin, sapogernin, flavanones, anthocyanin, flavan-3-ol, cyanogenic glycoside, ribalinidine, rutin, catechin, resveratol, spartein, epicatechin, steroid and phytate.
Conclusion: The highest concentration of bioactive components was sapogernin 23.1038µg/ml, while the lowest concentration 1.0565µg/ml consisted of Naringenin.
Aframomum melegueta (Alligator pepper); Bioactive components; Fourier-transform infrared spectroscopy (FTIR); Gas chromatography coupled with flame ionization detector (GCFID)
https://gscbps.gsconlinepress.com/sites/default/files/fulltext_pdf/GSCBPS-2023-…

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Uche Emmanuel Olunkwa, Kizito Munachiso Enyereibenyem Iheanacho, Chidi Uzoma Igwe, Linus Ahuwaraeze Nwaogu and Juliet Nkeiru Iheanacho. Bioactive component analysis of aqueous seed extract of Aframomum melengueta. GSC Biological and Pharmaceutical Sciences, 2023, 25(2), 249-272. Article DOI: https://doi.org/10.30574/gscbps.2023.25.2.0458


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