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Research and review articles are invited for publication in September 2026 - Vol. 36, Issue 3 

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Microfluidic organ-on-a-chip models of human lungs and heart: A review

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  • Microfluidic Organ-on-a-chip Models of Human Lungs and Heart: A Review
  • Microfluidic organ-on-a-chip models of human lungs and heart: A review

Vaishnavi Shivaji Apturkar *, Chaitanya Arvind Gulhane and Pramod Vitthalrao Burakale

Dr.Rajendra Gode institute of pharmacy Amravati, mardi road Amravati, Maharashtra, India.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 24(02), 205–214.
Article DOI: 10.30574/gscbps.2023.24.2.0329
DOI url: https://doi.org/10.30574/gscbps.2023.24.2.0329
Received on 04 July 2023; revised on 12 August 2023; accepted on 14 August 2023
A micro-physiological system is another term for an organ-on-a-chip. Due to the idea's widespread use in drug discovery, precision medicine, and drug screening, interest in it has increased recently. The primary message of this article is to illustrate how artificial drug proof can closely imitate the human body in every regard. Important work for a biomimetic system of physiological organs based on a microfluidic chip using cell biology, engineering, and biomaterials technology. In addition, the use and effectiveness of the gut-on-a-chip, liver-on-a-chip, lung-on-a-chip, and heart-on-a-chip are examined. We have discussed the current status of this project, OOC prospects for the future, and opportunities for microfluidic devices and organs on a chip in this section.
 
OOC- organ-on-a-chip; ECM- Extracellular matrix; PDMS- polydimethylsiloxane; PMMA- polymethylmethacrylate; cardiomyocytes; PILC- perfusion-incubator-liver-chip; interleukins; LOC- lab-on-a-chip
 
https://gscbps.gsconlinepress.com/sites/default/files/fulltext_pdf/GSCBPS-2023-…

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Vaishnavi Shivaji Apturkar, Chaitanya Arvind Gulhane and Pramod Vitthalrao Burakale. Microfluidic organ-on-a-chip models of human lungs and heart: A review. GSC Biological and Pharmaceutical Sciences, 2023, 24(2), 205-214. Article DOI: https://doi.org/10.30574/gscbps.2023.24.2.0329


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