1 Department of Radiation Oncology, S. N. Medical College, Agra (U.P), India.
2 Department of Microbiology, S. N. Medical College, Agra (U.P), India.
3 Department of Biochemistry, S. N. Medical College, Agra (U.P), India.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 22(03), 210–217.
Article DOI: 10.30574/gscbps.2023.22.3.0122
Received on 11 February 2023; revised on 22 March 2023; accepted on 25 March 2023
Introduction: Though with the invent of better diagnostic and therapeutic modalities the mortality rates due to cancer have fallen over the past years, but infection remains a primary or associated cause of death, with bacteria most commonly agent.
Objectives: This study was undertaken to monitor the types of pathogens commonly found in cancer patients undergoing anticancer treatment and their antibiotic resistance patterns.
Materials and methods: Total 100 patients, who were admitted for chemotherapy in department from 1 may 2021 to 31st July 2021 were enrolled and different samples were taken were sent to microbiology department for culture and sensitivity and then analysis was done.
Results: Maximum number of samples were of pus (26%) and sputum (26%), followed by urine sample, while blood and vaginal swab samples were least. Overall, 91% organism were gram negative bacteria. In pus samples, maximum no.of microbes found were klebsiella pneumoniae (37.03%) followed by E.coli (33.33%). In stool sample, commonest organism was klebsiella pneumoniae (50%) and in sputum, klebsiella pneumoniae was the most common found organism (57.69%), In urine, commonest organism was E.coli (66.66%) ,followed by klebsiella pneumoniae (33.33%). ESBL producing microbes were 69.09%, while ESBL non-producing were 30.9%.Highest resistance was seen with flouroquinolones(55%) while least with carbopenum(4%).
Conclusion: Judicial use of antibiotics, based on culture and sensitivity reports wherever possible, is of utmost importance so that further development of antibiotic resistance and infection related mortality can be reduced.
Samples; Microbes; Antibiotics; Resistance
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Surabhi Gupta, Arti Agrawal, Pratibha Kumari and Sarvesh Yadav. Pattern of bacterial infections in cancer patients: Experience from a Tertiary Cancer Center. GSC Biological and Pharmaceutical Sciences, 2023, 22(3), 210-217. Article DOI: https://doi.org/10.30574/gscbps.2023.22.3.0122