Effects of sweet potato (Ipomoea batatas) flour enriched with moringa (Moringa oleifera) leaf powder on erythrocyte and leukocyte haematological parameters and liver and kidney histology of albino rats (Rattus norvegicus) in the Haut-Sassandra region Côte

Diabetes is a pandemic with expensive treatments. It would be interesting to use locally available and inexpensive plants. Sweet potato tubers and moringa leaves are among them. The aim is to evaluate the impact of sweet potato flour enriched with moringa leaf powder on the haematological and histological parameters of albino rats. Four formulations based on sweet potato flour enriched with 5%, 10%, 15% and 20% moringa leaf powder, respectively BBPM5, BBPM10, BBPM15 and BBPM20. A dose of 300 mg/kg bw of each of these formulations was administered daily by gavage to rats versus controls given distilled water for 28 days. Haematological parameters were determined using the automated system and the impact assessed from histological sections. A non-significant increase in haemoglobin, red blood cell count, haematocrit, GMV and blood platelet count was observed in all treated lots. In addition, a non-significant decrease in MCHF and MCHR was observed. The hepatic and renal cells of the rats remained intact with the absence of hyperchromatosis in all batches except the control and BBPM5. At the end of this work, haematological parameters, liver and kidney tissues were not affected. The BBPM15 formulation appears to be the most effective and should be recommended to diabetics.