Determination of neutrophils to lymphocytes ratio, platelets count and mean platelet volume among patients with renal failure in Khartoum State

This is cross sectional study conducted in Khartoum state during the period from March 2019 to December 2019 to determine the effect of renal failure disease on Neutrophils to Lymphocytes Ratio, Platelets count and Mean Platelet Volume on Sudanese patients. One hundred and thirty-five 135 samples were collected from patients with renal failure disease 100 of them was chronic and 35 was acute, and thirty 30 samples from normal individuals as control, the age of patients between eighteen 18 and eighty 80 years, and not suffer from bleeding, heart diseases and liver diseases. 3 ml of venous blood samples were collected in ethylene diamine tetra acetic acid (EDTA) containers. The platelet count and Mean platelet volume were investigated using haematological analyser (sysmex KX-21N) and neutrophils to lymphocytes ratio (NLR) calculated by dividing the neutrophils by the lymphocytes, Data was analyzed by using statistical package for social science (SPSS) Version 20 and Excel worksheet. The neutrophils to lymphocytes ratio (NLR) was significantly increase among patients with renal failure when compared with normal individuals (P value=0.000). There were no significant differences in platelets count and mean platelet volume (MPV) between patients and normal individuals, P value (0.792) and (0.322) respectively. The study concluded that there is statistically significant increase in N/L ratio among patients with renal failure, so it can be used as a simple hematological marker for prognosis of disease, PLT count also showed significant difference between male and female in cases group.