Verification of analytical performance of alpha-fetoprotein assay on the Abbott Alinity ci®: Experience of the central laboratory of Mohammed VI University Hospital of Oujda

Imad-Eddine El khamlichi; Issam Mokhtari; Nisma Douzi; Oussama Grari; Soufiane Beyyoudh; Dounia El Moujtahide; El Houcine Sebbar; Mohammed Choukri

doi:10.30574/gscbps.2024.26.1.0035

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Verification of analytical performance of alpha-fetoprotein assay on the Abbott Alinity ci®: Experience of the central laboratory of Mohammed VI University Hospital of Oujda

Imad-Eddine El khamlichi ^{1, 2, *}, Issam Mokhtari ^{1, 2}, Nisma Douzi ^{1, 2}, Oussama Grari ^{1, 2}, Soufiane Beyyoudh ^{1, 2}, Dounia El Moujtahide ^{1, 2}, El Houcine Sebbar ^{1, 2} and Mohammed Choukri ^{1, 2}

1 Mohammed First University, Faculty of Medicine and Pharmacy of Oujda, Morocco.

2 Biochemistry laboratory of Mohammed VI University Hospital, Oujda, Morocco.

Research Article

GSC Biological and Pharmaceutical Sciences, 2024, 26(01), 291–297.

Article DOI: 10.30574/gscbps.2024.26.1.0035

DOI url: https://doi.org/10.30574/gscbps.2024.26.1.0035

Publication history

Received on 15 December 2023; revised on 21 January 2024; accepted on 24 January 2024

Abstract

The aim of our study was the verification of the analytical performance of alpha-fetoprotein determination on the Abbott CI analyzer utilizing the immuno-chemiluminescence method. The verification process was conducted in the biochemistry laboratory of Mohammed VI University Hospital of Oujda. The working methodology adapted is based on the recommendations of the protocol of the French accreditation committee (COFRAC) accreditation technical guide (GTA) 04, by the evaluation of reproducibility and repeatability. The results obtained by this evaluation were overall satisfactory and have meet the recommended criteria set by supplier and the French society of clinical biology. This study shows that the biochemistry laboratory of Mohammed VI University Hospital of Oujda can deliver an accurate and precise results which can be used for clinical diagnosis and decision making.

Keywords

Alpha-Fetoprotein assay; Analytical performance; Repeatability; Reproducibility; Alinity CI analyzer; Immuno-chemiluminescence

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Imad-Eddine El khamlichi, Issam Mokhtari, Nisma Douzi, Oussama Grari, Soufiane Beyyoudh, Dounia El Moujtahide, El Houcine Sebbar and Mohammed Choukri. Verification of analytical performance of alpha-fetoprotein assay on the Abbott Alinity ci®: Experience of the central laboratory of Mohammed VI University Hospital of Oujda. GSC Biological and Pharmaceutical Sciences, 2024, 26(1), 291-297. Article DOI: https://doi.org/10.30574/gscbps.2024.26.1.0035

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Verification of analytical performance of alpha-fetoprotein assay on the Abbott Alinity ci®: Experience of the central laboratory of Mohammed VI University Hospital of Oujda

Imad-Eddine El khamlichi ^{1, 2, *}, Issam Mokhtari ^{1, 2}, Nisma Douzi ^{1, 2}, Oussama Grari ^{1, 2}, Soufiane Beyyoudh ^{1, 2}, Dounia El Moujtahide ^{1, 2}, El Houcine Sebbar ^{1, 2} and Mohammed Choukri ^{1, 2}

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Verification of analytical performance of alpha-fetoprotein assay on the Abbott Alinity ci®: Experience of the central laboratory of Mohammed VI University Hospital of Oujda

Imad-Eddine El khamlichi 1, 2, *, Issam Mokhtari 1, 2, Nisma Douzi 1, 2, Oussama Grari 1, 2, Soufiane Beyyoudh 1, 2, Dounia El Moujtahide 1, 2, El Houcine Sebbar 1, 2 and Mohammed Choukri 1, 2

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Imad-Eddine El khamlichi ^{1, 2, *}, Issam Mokhtari ^{1, 2}, Nisma Douzi ^{1, 2}, Oussama Grari ^{1, 2}, Soufiane Beyyoudh ^{1, 2}, Dounia El Moujtahide ^{1, 2}, El Houcine Sebbar ^{1, 2} and Mohammed Choukri ^{1, 2}