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Research and review articles are invited for publication in September 2026 - Vol. 36, Issue 3 

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Phytochemical screening and evaluation of antibacterial activity of Olea europaea L.Var. sylvestris (Miller) Lear. leaves

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  • Phytochemical screening and evaluation of antibacterial activity of Olea europaea L.Var. sylvestris (Miller) Lear. leaves

Amel Zighed 1, *, Leila Derradji 1 and Youcef Hadef 2

1 Pharmacognosy Laboratory, Department of Pharmacy, Faculty of Medicine, Badji Mokhtar-Annaba University, Algeria.
2 Laboratory of Development and Control of Pharmaceutical Preparations, Department of Pharmacy, Faculty of Medicine, Badji Mokhtar-Annaba University, Algeria
Research Article
GSC Biological and Pharmaceutical Sciences, 2025, 33(02), 241-252.
Article DOI: 10.30574/gscbps.2025.33.2.0452
DOI url: https://doi.org/10.30574/gscbps.2025.33.2.0452
Received on 04 October 2025; revised on 12 November 2025; accepted on 15 November 2025
Olea europaea L.var. Sylvestris (Miller) Lehr., of the Oleaceae family, is commonly known as the wild olive tree. It is a tree used in traditional medicine in the Mediterranean region for its leaves, which contain numerous constituents with pharmacological properties such as hypoglycemic and anti-inflammatory properties. The objective of our work is to determine the qualitative chemical composition of the leaves of this species and to evaluate their antibacterial activity. The results we obtained after performing phytochemical screening of the methanolic extract of Olea europaea L.var. sylvestris leaves showed the presence of total polyphenols such as flavonoids and tannins, as well as sterols, triterpenes, and saponins. We evaluated the antibacterial activity of the methanolic extract of Olea europaea L.var. sylvestris using the agar diffusion method. The results obtained show that the leaves have moderate antibacterial activity. The most sensitive strains are Bacillus cereus ATCC 10876 and Pseudomonas aeruginosa ATCC 27853. Olea europaea L. var. sylvestris could be a solution to overcome bacterial resistance and is therefore of interest to public health.
Olea europaea L. var. sylvestris (Miller) Lehr; Methanolic leaf extract; Phytochemical screening; phenolic compounds; Antibacterial activity
https://gscbps.gsconlinepress.com/sites/default/files/fulltext_pdf/GSCBPS-2025-…

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Amel Zighed, Leila Derradji and Youcef Hadef. Phytochemical screening and evaluation of antibacterial activity of Olea europaea L.Var. sylvestris (Miller) Lear. leaves. GSC Biological and Pharmaceutical Sciences, 2025, 33(2), 241-252. Article DOI: https://doi.org/10.30574/gscbps.2025.33.2.0452


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