Home
GSC Biological and Pharmaceutical Sciences
Peer-reviewed Journal | Impact factor 8.1 | ISSN: 2581-3250 | CAS Source Indexed | Crossref DOI

Main navigation

  • Home
    • Journal Information
    • Editorial Board Members
    • Reviewer Panel
    • Abstracting and Indexing
    • Journal Policies
    • Our CrossMark Policy
    • Publication Ethics
    • Issue in Progress
    • Current Issue
    • Past Issues
    • Instructions for Authors
    • Article processing fee
    • Track Manuscript Status
    • Get Publication Certificate
    • Join Editorial Board
    • Join Reviewer Panel
  • Contact us
  • Downloads

Research and review articles are invited for publication in September 2026 - Vol. 36, Issue 3 

🌟 GSC Biological and Pharmaceutical Sciences (GSCBPS) 🌟

Low Publication Charges | Fast Editorial Processing | Crossref DOI Linking | Transparent Peer-Review Process

Publishing quality research in Biological Sciences, Pharmaceutical Sciences, Medicine, Healthcare and Allied Life Sciences.

e-ISSN: 2581-3250 | Impact Factor: 8.1 | Established: 2017 | Charges: USD 35 / INR 2100

📄 Submit Manuscript 👉 Author Guidelines 📚 Published Articles 

The influence of carbofuran insecticide exposure on the number of ovarian follicles in mice (Mus musculus)

Breadcrumb

  • Home
  • The Influence of Carbofuran Insecticide Exposure On The Number of Ovarian Follicles In Mice (Mus Musculus)
  • The influence of carbofuran insecticide exposure on the number of ovarian follicles in mice (Mus musculus)

Nur Muhammad Eka Iswahyudi, Eka Pramyrtha Hestianah, Widjiati, Maslichah Mafruchati and Epy Muhammad Luqman *

Department of Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Research Article
GSC Biological and Pharmaceutical Sciences, 2024, 26(01), 125–129.
Article DOI: 10.30574/gscbps.2024.26.1.0004
DOI url: https://doi.org/10.30574/gscbps.2024.26.1.0004
Received on 27 November 2023; revised on 06 January 2024; accepted on 08 January 2024
Objective: The aim of this research was to investigate the histopathological damage to the ovaries of mice (Mus musculus) caused by exposure to carbofuran.
Method: Twenty female mice aged 10 weeks with a body weight ranging from 25-30 mg were used in this study. The mice were divided into four groups, with each group consisting of five replicates. The control group (P0) received 0.5% physiological NaCl, while the treatment groups (P1, P2, and P3) were exposed to carbofuran at doses of 0.0833 mg/kg BW, 0.0417 mg/kg BW, and 0.0208 mg/kg BW, respectively, for ten days. On the 12th day, ovarian necropsy and HE staining were performed to observe the number of primary, secondary, tertiary, and Graafian follicles. Data analysis was conducted using ANOVA and BNJ tests.
Result: The results of this research showed that oral administration of carbofuran leads to a decrease in the number of secondary, tertiary, and Graafian follicles. High doses, such as 0.0833 mg/kg body weight, resulted in a more pronounced reduction in the number of secondary, tertiary, and Graafian follicles compared to the control group.
Conclusion: A reduction in the number of secondary, tertiary, and Graafian follicles with increasing doses of carbofuran.
Carbofuran; Mice; Ovarian; Follicles; Pesticide stress
https://gscbps.gsconlinepress.com/sites/default/files/fulltext_pdf/GSCBPS-2024-…

Preview Article PDF

Nur Muhammad Eka Iswahyudi, Eka Pramyrtha Hestianah, Widjiati, Maslichah Mafruchati and Epy Muhammad Luqman. The influence of carbofuran insecticide exposure on the number of ovarian follicles in mice (Mus musculus). GSC Biological and Pharmaceutical Sciences, 2024, 26(1), 125-129. Article DOI: https://doi.org/10.30574/gscbps.2024.26.1.0004


📝 Copyright, Licensing and Permissions: © Copyright Author(s). This article is published under the 🌐 Creative Commons Attribution 4.0 International License (CC BY 4.0) , which permits unrestricted use, distribution, adaptation, and reproduction in any medium, provided the original author(s) and source are properly credited, a link to the license is provided, and any changes made are indicated.


⚠️ Disclaimer: The statements, opinions, interpretations, and data presented in this publication are solely those of the individual author(s). GSC Biological and Pharmaceutical Sciences (GSCBPS), the editors, reviewers, editorial board, and publisher disclaim responsibility for any errors, omissions, or consequences arising from the use of the information contained in this article.


🏆 Get Publication Certificate 📄 Download Letter of Acceptance 🔗 Verify Crossref DOI 📘 View Issue Cover Page 👨‍🔬 Editorial Board 📑 Table of Contents 

🚀 Publish Your Research in International Peer Reviewed Open Access Journal - GSC Biological and Pharmaceutical Sciences (GSCBPS)

Submit your manuscripts from Biological Sciences, Pharmaceutical Sciences, Medicine, Healthcare, Biotechnology and Allied Life Sciences etc.

🌍 International Journal   |   👨‍🔬 Transparent Peer Review Process   |   🌐 Open Access Publishing   |   🔗 Crossref DOI 
⚡ Fast Editorial Processing   |   💰 Low Publication Charges

📝 Submit Your Manuscript 📘 Author Guidelines 💰 Publication Charges 

✅ No Submission Fee •  📜 Free Publication Certificate • 🌍 Global Visibility

⭐ Popular Pages


  • 🌍 International Journal
  • 🌐 Open Access Journal
  • 👨‍⚖️ Peer-Reviewed Journal
  • 💰 Low APC Journal
  • 🚀 Fast Publication Journal
  • ⚡ Fast-Track Peer-Review
  • 🔗 Crossref DOI Journal
  • 📖 Refereed Journal
  • 📈 High Impact Journal
  • 🧬 International Biology Journal
  • 💊 International Pharmacy Journal
  • 📝 Publish Research Paper

✍️ Author Resources


  • 📝 Publish Research Paper
  • 📖 Author Guidelines
  • 🎯 Aims and Scope
  • 💳 Article Processing Charges
  • 📤 Submit Manuscript
  • 📄 Cover Letter
  • ✍️ Author Declaration Form
  • 📄Track Manuscript Status
  • 📜 Get Publication Certificate
  • 📚 Journal Past Issue Archive
  • 🔎 Journal Indexing

⚖️ Journal Policies


  • ⚖️ Publication Ethics
  • 🛡️ Plagiarism Policy
  • 👨‍🔬 Peer Review Policy
  • 👨‍⚖️ Peer Review Process
  • 📖 Open Access Publishing
  • 📜 Copyright & Licensing
  • 🔗Author Self-Archiving Policy
  • 👥 Authorship Policy
  • 📊 Data Sharing Policy
  • 🤖 AI Usage Policy

Copyright © 2026 GSC Biological and Pharmaceutical Sciences - All rights reserved

Developed & Designed by VS Infosolution