1 Department of Pharmacognosy and Traditional Medicine, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria.
2 Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 24(01), 252–262.
Article DOI: 10.30574/gscbps.2023.24.1.0281
Received on 06 June 2023; revised on 15 July 2023; accepted on 18 July 2023
Dialium guineese is a plant traditionally used as anticancer, antioxidant, antiulcer, antidiarrhea and heart diseases. However, the pharmacognosy of this plant could be more explored. Therefore, we have conducted this study to assess the distinctive qualities of the D. guineese. The leaves were extracted using ethanol, the crude ethanol extract was then fractionated using solvents of increasing polarity (n-Hexane, ethyl acetate, butanol and aqueous) fraction. The qualitative and quantitative phytochemical constituents, microscopy, macroscopy, and physicochemical properties were performed based on standard procedures by World Health Organization (WHO).
Macro and microscopical studies showed the presence of an entire margin with an obovate shape, acuminate apex, rounded base, and calcium oxalate crystals. Stomata arrangement was paracytic with numerous trichomes on both surfaces while phytochemical evaluation revealed the presence of alkaloids, tannins, steroids and saponins. The investigations also included numerical and quantitative leaf microscopy.
In light of these discoveries, future research on the species will be able to accurately identify and authenticate it.
Dialium guineense; Phytochemical evaluation; Pharmacognostical studies and microscopic studies
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Cyril Onyeka Ogbue, Hope Morris Ifebi, Henriette Chinenye Nedum, Charity Chinasa Ezea and Chibueze Jeremiah Ike. Evaluation of the pharmacognostic profile of the leaves of Dialium guineeseWilld (Fabaceae) collected from Ukehe in Enugu state, Nigeria. GSC Biological and Pharmaceutical Sciences, 2023, 24(1), 252-262. Article DOI: https://doi.org/10.30574/gscbps.2023.24.1.0281