1 Biochemistry laboratory, University Hospital Center Joseph Ravoahangy Andrianavalona Madagascar.
2 University Hospital Center Mitsinjo Betanimena Tuléar Madagascar.
3 Medical Biology Student, Laboratory of Microbiology, University Hospital Center Joseph Ravoahangy Andrianavalona Madagascar.
4 Laboratory of Training and Research in Medical Biology, Madagascar.
Research Article
GSC Biological and Pharmaceutical Sciences, 2022, 19(02), 175–179.
Article DOI: 10.30574/gscbps.2022.19.2.0176
Received on 04 April 2022; revised on 12 May 2022; accepted on 14 May 2022
Introduction: C - reactive protein or CRP is an acute-phase protein of inflammation. CRP is of interest in the diagnosis and management of patients, particularly in paediatrics and in an infectious context. Our study aims at evaluating CRP in children under 15 years of age at the Biochemistry UPFR of the hospital CHU JRA.
Methods: This is a retrospective and descriptive study conducted at the Biochemistry UPFR of the hospital CHU JRA during 3 years. All analysis request forms containing a request for CRP dosage and belonging to patients under 15 years of age were included. All incompletely filled out forms and/or with missing or inaccurate clinical information were excluded from this study.
Results: A total of 476 cases were selected. A pathological CRP was found in 70.6% of cases. The sex ratio was 1.57. The average age was 6.67 years. Pathological CRP was found in 70.6% of cases, 25.0% of which were between 10 and 40 mg/L, 24.6% between 40 and 100 mg/L and 21.2% ≥ 100 mg/L. Infectious syndrome (26.3%), mainly fever, was the most common clinical finding. After the paediatric department (24.6%), CRP was prescribed by the emergency department (21.6%), oncology (12.6%), paediatric surgery (10.5%) and thoracic surgery (8.8%).
Conclusion: CRP dosage is a key test for suspected infectious diseases in order to make a therapeutic decision and also to determine the prognosis of the underlying disease.
CHU JRA; CRP; Infectious Syndrome; Paediatrics
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Miora Koloina RANAIVOSOA, Andriamiarimbola Irène RAKOTONIAINA, Andrianjakasolo Paulin RAZANAKOLONA and Andry RASAMINDRAKOTROKA. Evaluation of C - reactive protein among the pediatric population at the biochemistry UPFR of the hospital CHU RA from 2018 to 2020. GSC Biological and Pharmaceutical Sciences, 2022, 19(2), 175-179. Article DOI: https://doi.org/10.30574/gscbps.2022.19.2.0176