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Research and review articles are invited for publication in September 2026 - Vol. 36, Issue 3 

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Enhancing real-time infectious disease surveillance through AI-driven early warning and predictive outbreak detection systems

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  • Enhancing real-time infectious disease surveillance through AI-driven early warning and predictive outbreak detection systems

Lucky David Mayaki *

School of Health Studies, Northern Illinois University, USA.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2025, 33(03), 001–014.
Article DOI: 10.30574/gscbps.2025.33.3.0484
DOI url: https://doi.org/10.30574/gscbps.2025.33.3.0484
Received 21 October 2025; revised on 01 December 2025; accepted on 03 December 2025
The accelerating frequency and complexity of infectious disease outbreaks have exposed limitations in traditional surveillance systems, which often rely on delayed reporting, fragmented data streams, and resource-intensive manual analysis. To address these challenges, artificial intelligence (AI) is increasingly being integrated into public health infrastructure to enhance early detection, situational awareness, and real-time outbreak forecasting. AI-driven surveillance systems leverage machine learning, natural language processing, and spatiotemporal modeling to continuously monitor diverse data sources including electronic health records, laboratory submissions, social media signals, mobility patterns, and environmental indicators to identify anomalies that may signal emerging health threats. At a broader level, these systems enable national and global health agencies to shift from reactive responses to proactive, data-informed strategies that minimize transmission, optimize resource allocation, and support timely public health interventions. Progress in cloud computing, distributed data architectures, and edge AI has further enabled the deployment of real-time surveillance networks capable of processing high-velocity data with minimal latency. Within this framework, advanced predictive models such as recurrent neural networks, graph neural networks, and transformer-based architectures are increasingly used to estimate outbreak trajectories, detect subtle early warning patterns, and identify high-risk populations. At a more focused level, integrating AI tools into regional public health systems enhances the ability to predict localized outbreaks, automate case identification, and support precision epidemiology tailored to specific communities. Despite these advancements, challenges persist including data privacy concerns, algorithmic bias, limited interoperability across health systems, and disparities in digital infrastructure across low-resource settings. Addressing these constraints is essential to fully leverage AI-driven early warning systems as reliable, equitable, and scalable tools for global epidemic preparedness. Overall, AI-enabled surveillance holds transformative potential for strengthening health security and enabling faster, more precise outbreak prevention and control.
Artificial Intelligence; Infectious Disease Surveillance; Early Warning Systems; Predictive Outbreak Detection; Public Health Informatics; Real-Time Epidemiology
https://gscbps.gsconlinepress.com/sites/default/files/fulltext_pdf/GSCBPS-2025-…

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Lucky David Mayaki. Enhancing real-time infectious disease surveillance through AI-driven early warning and predictive outbreak detection systems. GSC Biological and Pharmaceutical Sciences, 2025, 33(3), 001-014. Article DOI: https://doi.org/10.30574/gscbps.2025.33.3.0484


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