1 Faculty of Pharmacy of Monastir. Tunisia.
2 Head of Department "C" of Diabetology and Nutritional Diseases- National Institute of Nutrition. Tunisia.
3 Director of the Biochemistry and Technobiology Research Laboratory. Faculty of Sciences of TunisLR01ES05. Tunisia.
4 Clinical Biochemistry Laboratory - National Institute of Nutrition Tunisia.
5 Biochemistry and Biotechnology Research Laboratory. Faculty of Sciences of Tunis. LR01ES05. Director of Department of Nutrition- Higher School of Health Sciences and Techniques of Tunis-Tunisia.
Research Article
GSC Biological and Pharmaceutical Sciences. 2023, 24(03), 056–067.
Article DOI: 10.30574/gscbps.2023.24.3.0359
Received on 26 July 2023; revised on 04September 2023; accepted on 07 September 2023
Introduction: Metabolic syndrome and diabetes are emerging diseases nowadays. so adjuvant therapy which is without harmful side effects has become the subject of various researches. Its beneficial effect has been proven however its place in the diet of obese subject remains to be dicovered. The subject of our work is to study the effects of flax seeds on lipids. insulin and ghrelin in women with type 2 diabetes with metabolic syndrome.
Method: We followed a population of 50 women with type 2 diabetes with metabolic syndrome who consumed 30g / d of flaxseed for 8 weeks. Then we compared the anthropometric and biochemical parameters at T0. T4 and T8 weeks. for the hormonal parameters we measured only between T0 and T8 because it is an expensive dosage.
Results: Improvement of the various parameters followed after consumption of flax seeds in our study group. This improvement is significantly better after 8 weeks. For glycemia. CT. TG. HDL-C. IMC. TT. PAS. PAD. insulinemia. ghrelinemia and resistinemia (p between 0.00 and 0.01 for all these parameters studied).
Discussion: Because of their high fibers and in SDG content. the flax seeds improve the anthropometric parameters. probably they favor a better glycemic profile by their richness in omega 3. The flax seen its contents rich in ALA shows an effectiveness to reduce the figures of the plasma lipids as well as the improvement of hormonal parameters.
Conclusion: In the end. this study. combined with the literature. allowed us to better understand the importance of the seeds of this plant in the diet of obese subjects with metabolic syndrome. Enriching your diet with these seeds would therefore be an effective means in the fight against obesity and metabolic syndrome.
Diabetes mellitus; Lipids; Ghrelin; Insulin; Metabolic syndrome
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Amna Sleimi, Amine Abbassi, Faika Ben Mami, Kame Ben Mahrez l, Mohamed.Chiheb Ben Rayana, Amina Bibi and Fethi Ben Slama. Effect of flax seeds on lipids: Insulin and ghrelin in type 2 diabetic women with metabolic syndrome. GSC Biological and Pharmaceutical Sciences, 2023, 24(3), 056-067. Article DOI: https://doi.org/10.30574/gscbps.2023.24.3.0359