Determination of hemoglobin level, mean cell volume and red cell distribution width among patients with renal failure in Khartoum state

As a body fluid, blood supplies nutrients and oxygen to cells and carries away metabolic waste products. A cross-sectional study was conducted between February and April 2021 in Khartoum state to examine the effect of renal failure on hemoglobin level, mean cell volume (MCV), and red cell distribution width (RDW) in Sudanese patients. One hundred and thirty-five samples were collected from patients with renal failure, 100 of them were chronic, 35 were acute, and thirty 30 samples were from normal individuals as control, the age of patients between eighteen 18 and eighty 80 years, all the selected participants were not suffering from heart diseases or liver diseases.3 ml of venous blood samples were collected in ethylene diamine tetra acetic acid (EDTA) containers. The haemoglobin, MCV, and RDW were investigated using a haematological analyzer (Sysmex KX-21N).

The hemoglobin level was significantly low among patients with renal failure compared to normal individuals (P value=0.011). While no significant differences in mean cell volume (MCV) and red cell distribution width (RDW) between patients and normal individuals, with P-values (0.842) and (0.254) respectively. The study results reveal that the haemoglobin levels are lower in patients with kidney failure than in healthy individuals. Additionally, the haemoglobin levels decrease as the patient progresses into chronic renal failure in contrast to acute renal failure.