Clinical and biochemical of Foot temperature in diabetic patients

Elevated foot temperature is a frequently observed symptom among individuals with diabetes, commonly attributed to peripheral neuropathy. In contrast, impaired kidney function represents a major chronic complication associated with diabetes. This study focuses on evaluating the influence of diabetes on renal function and its potential link to increased foot temperature. Participants included individuals diagnosed with either type 1 or type 2 diabetes, ranging from 25 to 75 years of age. Blood samples were collected and processed using gel tubes for serum isolation through centrifugation at 4000 rpm to facilitate biochemical analysis. Additional blood samples were preserved in EDTA tubes for the assessment of glycated hemoglobin (HbA1C). The study involved a total of 100 participants, comprising 75 diabetic patients and 25 healthy individuals serving as the control group. Investigations included quantifying accumulated blood glucose and assessing renal function parameters. The results showed a relationship between HbA1c levels and kidney function, with values of urea p value 0.02, creatinine p0.018, and blood glucose p0.001. Age also played a role in kidney function, with values of urea p value0.021 and creatinine p value0.049. Regarding gender, the results showed that the prevalence of diabetes was higher in men than women, at 57.1% compared to 42.9% in women. Conclusion declining kidney function is a significant chronic complication of diabetes. The relationship between the two is evident in that chronic disruption of blood sugar control leads to microvascular damage.